INDICATIONS

 BIOCHEMISTRY OF ENOS

 CARDIOVASCULAR
  • Overview
  • Basic Facts

 ALZHEIMER'S DISEASE

 STROKE


Cardiovascular Basic Facts

Incidence
 Since 1900, cardiovascular disease (CVD) has been the number one killer in the US every year but 1918
 More than 2,600 Americans die of CVD each day: about 1 death every 33 seconds
 CVD claims almost 10,500 more lives each year than the next six leading causes of death combined
 CVD is a global problem:
The Russian Federation has the highest rate of death due to CVD: 1310 per 100,000 population
Among industrialized nations, Japan has the lowest death rate due to CVD: 201 per 100,000 population
Over a 16-year period, the CVD age-adjusted death rate declined about 30%, from 530 to 375 deaths per 100,000 Americans

Demographics
 About 1 in 5 Americans has some form of cardiovascular disease
 85% of people who die of coronary heart disease (CHD) are 65 or older
 This year about 1.1 million Americans will have a new or recurrent coronary attack; more than 40% of these will die
 Under age 75, more men have coronary heart disease; more women have congestive heart failure (CHF)
 Smoker's risk versus nonsmoker's:
Two-fold higher risk of suffering a heart attack
Two- to four-fold higher risk of suffering sudden cardiac death
More likely to die within one hour of having a heart attack

Impact
 In 1997, $26.9 billion in payments were made to Medicare beneficiaries for hospital expenses due to cardiovascular problems; this represents an average of $7,873 per discharge.
 In 1997, 25.8% of nursing home residents age 65 or older had a primary diagnosis of CVD at admission
 Estimated costs of cardiovascular diseases in the US:
Direct costs, including hospital/nursing home, physicians/other professional care, drugs/other medical durables, and home health care: $153.8 billion
Indirect costs, including lost productivity because of morbidity and mortality: $99 billion
Total estimated direct and indirect costs of CVD: $252.8 billion




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